Response to ‘When biostatistics is a neo-inductionist barrier to science’

How Political Science Can Contribute to Public Health: A Response to Gagnon and Colleagues

Immune response to mutant neo-antigens

Extending observations on the immunogenicity of neo-antigens that arise in the course of oncogenesis and tumor progression, we suggest that somatic mutations affecting normal tissues also lead to generation of new epitopes. We hypothesize that, at least under inflammatory conditions, immune responses against such neo-antigens may lead to the elimination or functional impairment of normal cells,...

The Ottoman Response to the Western Storm: Lessons for Neo-Ottomanism in Turkey

How to Use MRP in Continuous Production Industries When Order Type is Lot for Lot

The Materials Requirements Planning (MRP) method that is applied in production planning and management has some weaknesses. One of its weaknesses is that the time in MRP method is discrete, and is considered as time period. Hence we are not able to order our requirements at irregular time moments or periods. In this paper, a new form of MRP is introduced that is named Continuous Materials Requi...

Is Tc99m-MIBI scintigraphy a predictor of response to pre-operative neoadjuvant chemotherapy in Osteosarcoma?

Objectives: Multidrug resistance (MDR), which may be due to the over expression of P-glycoprotein (Pgp) and/or MRP, is a major problem in neoadjuvant chemotherapy of osteosarcoma. The aim of this study was to investigate the role of Tc-99m MIBI scan for predicting the response to pre-operative chemotherapy. Materials and Methods: Twenty-five patients (12 males and 13 females, aged between 8 and...